I saw this topic on a Gamefaqs board, and I hate posting there at all, as it's a very toxic "community" so I figured I'd post it here. I'd much rather know what your favorites are, compared to a bunch of people I know nothing about. I'll start...
NES - Crystalis
SNES - TLoZ: A Link to the Past
N64 - TLoZ: Ocarina of Time
Gamecube - Super Mario Sunshine
Wii - Xenoblade Chronicles
Wii U - TLoZ: Wind Waker HD
Switch - TLoZ: Breath of the Wild (Could be knocked down by Xenoblade Chronicles 2)
GB - TLoZ: Link's Awakening
GBC - TLoZ: Oracle of Ages
GBA - Golden Sun: The Lost Age
DS - Chrono Trigger DS
3DS - Hyrule Warriors Legends
Genesis - Sonic the Hedgehog 2
Playstation - Legend of Dragoon
PS2 - Star Ocean: Till the End of Time
PC - Megadimension Neptunia VII
PSP - The Legend of Heroes: A Tear of Vermillion